REVIEW

Out in Theaters: SIDE EFFECTS

Name: Side Effects review
Item: Side Effects
Rating: 3.7
Author: Matt Oakes

By Matt Oakes · February 11, 2013

Where to watch: Streaming on Prime Video and Paramount+, free on The Roku Channel, Kanopy, Pluto TV and Tubi, or rent or buy on digital (updated October 2026)Watch on Prime Video · Watch on Paramount+ · Watch on The Roku Channel · Watch on Kanopy · Watch on Pluto TV · Watch on Tubi · Rent or buy on Amazon · Buy on Blu-ray/4KAs an Amazon Associate, Silver Screen Riot earns from qualifying purchases.

“Side Effects“
Directed by Steven Soderbergh
Starring Jude Law, Rooney Mara, Catherine Zeta-Jones, Channing Tatum
Crime, Drama, Thriller
106 Mins
R

With Side Effects, Steven Soderbergh (Ocean’s Eleven) hasn’t reinvented the thriller, he’s just breathed life back into a fading genre. What begins as an ambiguous tale of a struggling romance morphs into a pulsing question mark whose greatest strengths lie within it’s ability to create suspense and uncertainty.

▶ Streaming on Prime Video. More picks: The Best Thriller Movies on Prime Video Right Now →

Since the twists and turns are vital to your general enjoyment of the film, I want to carefully navigate to ensure that nothing here is too telling. All you really need to know is that the story opens with Rooney Mara (The Girl With the Dragon Tattoo) reuniting with her husband Channing Tatum (Magic Mike) and from there delves quickly and fervently into the world of psychiatry and prescription pills.

Filling out the cast we have Jude Law (Sherlock Holmes) playing a psychiatrist struggling with a puzzle of a patient. He has a great little character arc that is handled with subtle panache, pulling a muted transformation in the most understated of ways. His new client puts him in contact with a fellow colleague played by Catherine Zeta Jones (The Mask of Zorro) who has an unwritten history with Law’s patient. Although we don’t see Jones that often on screen anymore, she shows that she’s still gotta talent within her 40-something sex appeal.

All four of the principal characters are putting their all in here and I’d expect nothing less under the lead of Soderbergh. He has a crisp, clear direction and a really deliberate framing. All of his shots are captured with concise precision. Nothing here feels left to chance as little bits of foreshadowing are dug intricately into the scenery for those watching with a careful eye.

Soderbergh has talked at length about how he felt Side Effects was the natural progression of the thriller which he asserts have died out in the past few decades. To a degree, he’s right. As an audience, we’re not accustom to the suspense builders than dominated the silver screen of the ’80s and ’90s and so something like Side Effects is a pleasant throwback.

In the same vein though, it fails to really transcend the trappings of the genre and provide anything groundbreaking. And while you can applaud it’s level of self restraint, both within the acting and directing field, it just doesn’t have the staying power of films that transcend their genres. While it truly is a completely competent and very well acted, nothing here feels new or remarkable. It’s a great suspense thriller just not a genuinely great movie.

There’s enough backstabbing, lies, betrayals and revelations to keep Side Effects tautand the audience on the edge of their seats. It’s a rare thriller that manages to deliver on the thrills and much like the thrillers of the ’80s and ’90s it will keep you engaged for its runtime but is unlikely to stay with you long after.

Follow Silver Screen Riot on Facebook
Follow Silver Screen Riot on Twitter